ABSTRACT

Since stroke is the third leading cause of death in the United States and the major cause of disability in older individuals, prevention deserves greater and more dedicated efforts by medical practitioners and health policy planners. As the population continues to age, successful implementation of stroke prevention strategies should produce tangible benefits for large segments of society.

The Prevention of Stroke focuses on the stroke risk factors that are amenable to modification and describes ongoing strategies for their amelioration. It emphasizes primary prevention of risk factors because intervention before a stroke risk factor appears clinically is likely to yield the highest benefits. It also recognizes secondary prevention measures as important in reducing the chance of a stroke. A strength of this book is its reliance on well-founded, scientifically derived evidence interpreted by clinically experienced stroke experts. The authors assess the state of our current knowledge of successful stroke prevention measures while pointing out areas where there is a need to develop new and better prevention techniques. With a fund of bibliographic references and comprehensive index, this is an essential clinical reference on the successful prevention of stroke.

chapter 1|10 pages

Stroke incidence, mortality, and prevalence

George Howard, and Virginia J. Howard,

chapter 2|10 pages

‘Nonmodifiable’ risk factors for stroke: age, race, sex, and geography

Virginia J. Howard, and George Howard,

chapter 4|9 pages

Cardiac disease and risk of ischemic stroke

Richard F. Gillum,

chapter 5|16 pages

Inflammation, infection and homocysteine in atherosclerosis

Thomas J. DeGraba,

chapter 6|17 pages

Stroke in sickle cell disease

Sung B. Lee, and Robert J. Adams,

chapter 7|9 pages

Oral contraception and postmenopausal estrogen replacement therapy

Gretchen E. Tietjen, , and Robin L. Brey,

chapter 8|12 pages

Genetics and stroke

John W. Cole, , and Steven J. Kittner,

chapter 9|10 pages

Markers of subclinical vascular disease and stroke

Monika Hollander, and Monique M.B. Breteler,

chapter 10|7 pages

Community mass and high risk strategies

Philip B. Gorelick,

chapter 11|8 pages

Stroke prevention in managed care: a five-dimensional health improvement model

Meredith L. Tipton, , and Michael Fleming,

chapter 12|10 pages

National, state and local opportunities for stroke prevention

Darwin R. Labarthe, and Miriam M. Fay,

chapter 13|7 pages

Quality improvement in stroke prevention

Robert G. Holloway, and Steven R. Rush,

chapter 15|7 pages

Stroke and public policy: the role of stroke advocacy groups

Patti Shwayder,

chapter 16|6 pages

I. Hypertension treatment

William J. Elliott, , Jay Garg, , and Munavvar Izhar,

chapter II|4 pages

Smoking cessation

Philip B. Gorelick,

chapter 17|9 pages

Hyperlipidemia and diabetes mellitus

Ambika Babu, , Chakravarthy Kannan, , and Theodore Mazzone,

chapter 18|10 pages

Ethanol consumption and physical inactivity

William J. Elliott,

chapter 19|15 pages

I. Antiplatelet therapies for prevention of first and recurrent stroke

Stanley N. Cohen,

chapter II|14 pages

Anticoagulation for stroke prevention

Michael J. Schneck,

chapter 20|10 pages

Carotid endarterectomy for symptomatic and asymptomatic carotid stenosis

James D. Fleck, , and José Biller,

chapter 22|6 pages

Pros and cons of screening for and ablating asymptomatic intracranial aneurysms

Sean Ruland, , and Dan Heffez,

chapter 23|3 pages

Closing remarks: on stroke prevention guidelines, organization of care and future perspectives

Edward H. Wong, , and Vladimir Hachinski,