ABSTRACT

The Handbook of Assay Development in Drug Discovery describes all the tools currently available for performing various assay techniques. Featuring troubleshooting advice for common problems from experienced assay developers, the vendor community, and scientists in the pharmaceutical industry, the book presents descriptions of methods, laboratory guidelines and protocols used to perform such methods, specific examples of each assay system, and troubleshooting tools. Designed as a guide to running an assay from start to finish, this is an ideal bench top companion for scientists involved in drug discovery screening, lead profiling, therapeutic target evaluation, and assay development and implementation.

chapter 7|12 pages

IMAP Assays for Protein Kinases

chapter 9|12 pages

Proteases as Drug Targets

chapter 13|10 pages

Nuclear Receptors as Drug Targets

chapter 24|24 pages

Aurora Assays