ABSTRACT

Kucers’ The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference.

Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with expert contributors representing Europe, Africa, Asia, Australia, South America, the US, and Canada, the Seventh Edition adopts a truly global approach. It remains invaluable for anyone using antimicrobial agents in their clinical practice and provides, in a systematic and concise manner, all the information required when prescribing an antimicrobial to treat infection.

section 2|2545 pages

Antibiotics

part 2_1|324 pages

Penicillins and Related Drugs

chapter 6|7 pages

Methicillin

chapter 8|11 pages

Nafcillin

chapter 12|7 pages

Temocillin

chapter 14|26 pages

Amoxicillin–Clavulanic Acid

chapter 16|20 pages

Ticarcillin–Clavulanic Acid

chapter 17|26 pages

Piperacillin–Tazobactam

part 2_2|315 pages

Cephalosporins and Related Drugs

chapter 19|9 pages

Cephalexin

chapter 22|13 pages

Cefuroxime

chapter 26|38 pages

Cefotaxime

chapter 27|66 pages

Ceftriaxone

chapter 29|9 pages

Cefixime

chapter 33|17 pages

Ceftobiprole

chapter 35|14 pages

Aztreonam and Aztreonam-Avibactam

chapter 36|2 pages

Cefiderocol (S-649266)

part 2_3|122 pages

Carbapenems

part 2_4|164 pages

Glycopeptides and Lipopeptides

chapter 43|51 pages

Vancomycin

chapter 44|30 pages

Teicoplanin

chapter 45|42 pages

Daptomycin

chapter 46|9 pages

Oritavancin

chapter 47|13 pages

Dalbavancin

chapter 48|10 pages

Telavancin

chapter 49|4 pages

Ramoplanin

chapter 50|3 pages

Surotomycin

part 2_5|116 pages

Aminoglycosides

chapter 51|15 pages

Kanamycin

chapter 52|28 pages

Gentamicin

chapter 53|17 pages

Tobramycin

chapter 54|19 pages

Amikacin

chapter 55|11 pages

Sisomicin and Netilmicin

chapter 56|7 pages

Isepamicin

chapter 57|7 pages

Neomycin

chapter 58|10 pages

Plazomicin

part 2_6|129 pages

Macrolide and Ketolides

chapter 59|22 pages

Erythromycin

chapter 60|10 pages

Roxithromycin

chapter 61|25 pages

Clarithromycin

chapter 62|28 pages

Azithromycin

chapter 63|6 pages

Josamycin and Rosaramicin

chapter 64|13 pages

Telithromycin

chapter 65|7 pages

Cethromycin

chapter 66|13 pages

Solithromycin

part 2_7|97 pages

Tetracyclines and Related Drugs

chapter 67|9 pages

Tetracycline

chapter 68|26 pages

Doxycycline

chapter 69|19 pages

Minocycline

chapter 70|18 pages

Tigecycline

chapter 71|6 pages

Omadacycline

chapter 72|17 pages

Eravacycline

part 2_8|276 pages

Other Antibiotics

chapter 73|55 pages

Linezolid

chapter 74|6 pages

Cadazolid

chapter 75|2 pages

Radezolid

chapter 76|18 pages

Tedizolid

chapter 77|12 pages

Quinupristin–Dalfopristin

chapter 78|6 pages

Pristinamycin

chapter 79|15 pages

Fosfomycin

chapter 80|11 pages

Fusidate Sodium

chapter 81|30 pages

Polymyxins

chapter 82|4 pages

Novobiocin

chapter 83|6 pages

Bacitracin and Gramicidin

chapter 84|8 pages

Mupirocin

chapter 85|47 pages

Clindamycin and Lincomycin

chapter 86|27 pages

Chloramphenicol and Thiamphenicol

chapter 87|5 pages

Spectinomycin

chapter 88|9 pages

Fidaxomicin

chapter 89|5 pages

Lefamulin

chapter 90|7 pages

Retapamulin

part 2_9|236 pages

Antifoliate Agents and Other Synthetic Antibacterials

part 2_10|58 pages

Nitroimidazoles

chapter 99|43 pages

Metronidazole

chapter 100|13 pages

Tinidazole

part 2_11|456 pages

Quinolones and Fluoroquinolones

part 2_11A|303 pages

New and Commonly Used Fluoroquinolones

chapter 101|119 pages

Ciprofloxacin

chapter 102|18 pages

Norfloxacin

chapter 103|51 pages

Ofloxacin

chapter 104|30 pages

Levofloxacin

chapter 105|25 pages

Moxifloxacin

chapter 106|12 pages

Gemifloxacin

chapter 107|10 pages

Sitafloxacin

chapter 109|8 pages

Finafloxacin

part 2_11B|150 pages

Older, Rarely Used Quinolones and Fluoroquinolones

chapter 112|9 pages

Enoxacin

chapter 113|15 pages

Fleroxacin

chapter 114|18 pages

Garenoxacin

chapter 115|32 pages

Gatifloxacin

chapter 116|9 pages

Lomefloxacin

chapter 117|23 pages

Nalidixic Acid and Other Quinolones

chapter 118|13 pages

Pefloxacin

chapter 119|4 pages

Rufloxacin

chapter 120|10 pages

Sparfloxacin

chapter 121|5 pages

Tosufloxacin

chapter 122|10 pages

Discontinued Fluoroquinolones

part 2_12|245 pages

Anti-Tuberculous Drugs

chapter 123|25 pages

Isoniazid

chapter 124|15 pages

Ethambutol

chapter 125|8 pages

Pyrazinamide

chapter 126|65 pages

Rifampicin (Rifampin)

chapter 127|16 pages

Rifabutin

chapter 128|13 pages

Rifaximin

chapter 129|8 pages

Rifapentine

chapter 130|17 pages

Streptomycin

chapter 132|10 pages

Ethionamide and Prothionamide

chapter 133|7 pages

Thiacetazone

chapter 134|10 pages

Capreomycin

chapter 135|11 pages

Cycloserine and Terizidone

chapter 136|2 pages

Viomycin

chapter 137|9 pages

Clofazimine

chapter 138|8 pages

Bedaquiline

chapter 139|9 pages

Delamanid and Pretomanid

chapter 140|5 pages

Sutezolid

section 3|371 pages

Antifungal Drugs

part 3_1|89 pages

3:1 Polyenes

chapter 144|7 pages

Nystatin

chapter 145|3 pages

Natamycin

part 3_2|50 pages

Echinocandins

part 3_3|21 pages

Allylamines and Benzylamine Derivatives

chapter 149|11 pages

Terbinafine

chapter 151|3 pages

Naftifine

part 3_4|154 pages

Systemic Azoles

chapter 152|25 pages

Ketoconazole

chapter 153|30 pages

Fluconazole

chapter 154|26 pages

Itraconazole

chapter 155|11 pages

Miconazole

chapter 156|20 pages

Voriconazole

chapter 157|15 pages

Posaconazole

chapter 159|6 pages

Albaconazole

part 3_5|15 pages

Topical Azoles

chapter 161|13 pages

Topical Azoles

part 3_6|17 pages

Topical Agents-Thiocarbomates, Hydroxypyridones, And Morpholine

chapter 162|3 pages

Tolnaftate

chapter 163|5 pages

Amorolfine

chapter 164|5 pages

Ciclopirox

chapter 165|2 pages

Rilopirox

part 3_7|19 pages

Other Antifungal Agents

chapter 167|6 pages

Griseofulvin

chapter 168|3 pages

Haloprogin

section 4|508 pages

Antiparasitic Drugs

part 4_1|208 pages

Anti-Malarial Drugs

chapter 172|17 pages

Dihydroartemisinin–Piperaquine

chapter 173|13 pages

Pyronaridine–Artesunate

chapter 176|9 pages

Amodiaquine

chapter 178|16 pages

Mefloquine

chapter 179|6 pages

Halofantrine

chapter 180|13 pages

Primaquine

chapter 181|7 pages

Tafenoquine

chapter 182|10 pages

Atovaquone

chapter 183|9 pages

Proguanil and Chlorproguanil

chapter 184|11 pages

Atovaquone–Proguanil

part 4_2|56 pages

Agents Active Against Intestinal and Extra-Intestinal Protozoa

chapter 185|13 pages

Paromomycin

chapter 186|13 pages

Nitazoxanide

chapter 187|8 pages

Spiramycin

chapter 188|4 pages

Fumagillin

chapter 190|5 pages

Diloxanide Furoate

chapter 191|3 pages

Iodoquinol and Quinacrine

part 4_3|19 pages

Agents Active Against American Trypanosomiasis

chapter 192|6 pages

Benznidazole

chapter 193|11 pages

Nifurtimox

part 4_4|46 pages

Agents Active Against African Trypanosomiasis

chapter 194|12 pages

Suramin

chapter 195|16 pages

Melarsoprol

chapter 196|16 pages

Eflornithine

part 4_5|41 pages

Agents Active Against Leishmania and other Pathogens

chapter 197|9 pages

Pentamidine

chapter 198|12 pages

Antimonial Agents

chapter 199|18 pages

Miltefosine

part 4_6|99 pages

Agents Active Against Helminths

chapter 200|17 pages

Albendazole

chapter 201|8 pages

Mebendazole

chapter 202|9 pages

Thiabendazole and Flubendazole

chapter 203|4 pages

Triclabendazole

chapter 204|19 pages

Ivermectin and Moxidectin

chapter 207|12 pages

Praziquantel

chapter 208|8 pages

Oxamniquine and Metrifonate

chapter 209|5 pages

Niclosamide

part 4_7|34 pages

Agents Active Against Ectoparasites

section 5|1201 pages

Antiviral Drugs

part 5_1|205 pages

Agents Active Against Herpesviruses

chapter 217|10 pages

Brivudin

chapter 219|33 pages

Foscarnet

chapter 221|7 pages

Trifluridine (Trifluorothymidine)

chapter 222|6 pages

Idoxuridine

chapter 223|7 pages

Maribavir

chapter 224|5 pages

Fomivirsen

part 5_2|668 pages

Agents Active Against the Human Immunodeficiency Virus

part 5_2A|198 pages

Nucleoside Reverse Transcriptase Inhibitors

chapter 225|41 pages

Zidovudine

chapter 226|25 pages

Didanosine

chapter 227|6 pages

Zalcitabine

chapter 228|26 pages

Lamivudine

chapter 229|18 pages

Stavudine

chapter 230|28 pages

Abacavir

chapter 231|22 pages

Emtricitabine

chapter 232|24 pages

Tenofovir

chapter 233|3 pages

Amdoxovir

chapter 234|3 pages

Apricitabine

part 5_2B|164 pages

Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)

chapter 235|52 pages

Nevirapine

chapter 236|52 pages

Efavirenz

chapter 237|11 pages

Delavirdine

chapter 238|19 pages

Etravirine

chapter 239|28 pages

Rilpivirine

part 5_2C|191 pages

Inhibitors of HIV Protease

chapter 240|37 pages

Saquinavir

chapter 241|12 pages

Indinavir

chapter 242|9 pages

Nelfinavir

chapter 243|13 pages

Lopinavir

chapter 244|17 pages

Fosamprenavir

chapter 245|14 pages

Darunavir

chapter 246|14 pages

Atazanavir

chapter 247|19 pages

Tipranavir

chapter 248|28 pages

Ritonavir and Cobicistat

part 5_2D|80 pages

Integrase Inhibitors

chapter 249|24 pages

Raltegravir

chapter 250|15 pages

Elvitegravir

chapter 251|34 pages

Dolutegravir

part 5_2E|26 pages

Other Anti-HIV Agents

chapter 252|8 pages

Enfuvirtide

chapter 253|12 pages

Maraviroc

part 5_3|199 pages

Agents Active Against Hepatitis Viruses

chapter 254|11 pages

Entecavir

chapter 255|10 pages

Adefovir Dipivoxil

chapter 256|11 pages

Telbivudine

chapter 259|42 pages

Ribavirin

chapter 260|23 pages

Interferon Alpha

part 5_4|105 pages

Agents Active Against Influenza Viruses

chapter 265|20 pages

Amantadine and Rimantadine

chapter 267|24 pages

Oseltamivir

chapter 268|14 pages

Peramivir

part 5_5|19 pages

Investigational Antiviral Drugs