ABSTRACT
Stem cells potentially offer a novel therapeutic platform to treat bone disease. They also help the scientist understand the molecular and cellular aetiology of bone disorders. Gaining knowledge on the nature and application of stem cell sciences is a prerequisite for understanding their potential in treating or preventing bone disorders. Stem Cell
TABLE OF CONTENTS
part |2 pages
Section 1 Introductory Text and Sources of Stem Cells for Skeletal Tissue
chapter 1|19 pages
Endothelial Progenitor Cell-based Therapy for Orthopaedic Regenerative Medicine
Ru Li,* Aaron Nauth, Nizar Mahomed, Darrell Ogilvie-Harris and Emil Schemitsch
chapter 2|22 pages
Transplanted Bone Marrow Stromal Cells and Bone Tissue Regeneration
Qisheng Tu and Jake Chen*
chapter 3|20 pages
Isolation and Puriϐication Methods for Mesenchymal Stem
Kristen P. McKenzie, Dana C. Mayer and Jane E. Aubin
chapter 4|18 pages
The Human Nose Offers a New Stem Cell Source for Bone Injuries
Pierre Layrolle, Bruno Delorme, Francois Feron* and Emmanuel Nivet*
chapter 5|21 pages
Multipotential Mesenchymal Stromal/Stem Cells in Skeletal Tissue Repair
Agnieszka Arthur, Andrew Zannettino and Stan Gronthos
chapter 6|20 pages
Adipose-derived Stem Cells (ASCs) and Bone Repair: An Overview in Regenerative Medicine
Natalina Quarto* and Michael T. Longaker
part |2 pages
Section 2 Cellular and Molecular Aspects
chapter 7|20 pages
The Modulation of Skeletal Stem Cell Function Through Nanoscale Topography
Manus J.P. Biggs* and Laura E. McNamara
chapter 8|16 pages
Myostatin (GDF-8) Signaling in Progenitor Cells and Applications to Bone Repair
Moataz N. Elkasrawy and Mark W. Hamrick*
chapter c|19 pages
c-Jun-centred Regulatory Network of Signalling Pathways in Bone Stem Cells and Applications to Bone Repair
Jon Fernández-Rueda, Emma Jakobsson, Akaitz Dorronsoro and César Trigueros*
chapter 10|20 pages
Endothelial Progenitor Cells, Lnk and Bone Fracture
Tomoyuki Matsumoto* and Takayuki Asahara
chapter 11|14 pages
Stromal Cell-derived Factor 1/CXCR4 Signaling, Stem Cells, and Fractures
Hiromu Ito
chapter 12|15 pages
Chromatin Remodeling and Transcriptional Control of Mesenchymal Cells Towards the Osteogenic Pathway
Marom R. and Benayahu D.*
part |2 pages
Section 3 Conditions, Applications, Treatments and Repairs
chapter 14|22 pages
Allogeneic Mesenchymal Stem Cells for Bone Tissue Engineering: Clinical and Basic Research on Perinatal Hypophosphatasia
Hiroe Ohnishi, Yoshihiro Katsube, Mika Tadokoro,
chapter 15|22 pages
Haematopoietic Stem Cell Transplantation in Autosomal Recessive Osteopetrosis
Anna Teti* and Ansgar S. Schulz
chapter 16|18 pages
Human Fetal Stem Cells and Osteogenesis Imperfecta
Gemma N. Jones and Pascale V. Guillot*
chapter 17|19 pages
G-CSF-mobilized Haploidentical Peripheral Blood Stem Cell Transplantation in Childhood Osteopetrosis
Fikret Arpaci* and Asli Selmin Ataergin
chapter 18|23 pages
Combining Osteochondral Stem Cells and Biodegradable Hydrogels for Bone Regeneration
Matilde Bongio, Wanxun Yang, Fang Yang, Sanne K. Both, Sander C.G. Leeuwenburgh, Jeroen
chapter 20|21 pages
Transplantation of Human Adipose-derived Stem Cells for Fracture Healing: Multi-lineage Differentiation Potential and Paracrine Effects
Taro Shoji, Masaaki Ii and Takayuki Asahara*
