ABSTRACT
Design and Analysis of Clinical Trials for Predictive Medicine provides statistical guidance on conducting clinical trials for predictive medicine. It covers statistical topics relevant to the main clinical research phases for developing molecular diagnostics and therapeutics-from identifying molecular biomarkers using DNA microarrays to confirming
TABLE OF CONTENTS
part |2 pages
Section I Introductory Overview
part |2 pages
Section II Early Clinical Trials Using Biomarkers
part |2 pages
Section III: Phase III Randomized Clinical Trials Using Biomarkers
part |2 pages
Section IV: Analysis of High-Dimensional Data and Genomic Signature Developments
part |2 pages
Section V: Randomized Trials with Biomarker Development and Validation
part |2 pages
Section VI Evaluation of Surrogate Biomarkers
