ABSTRACT

Intravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or undergoing clinical trials. The technique of prolonged intravenous delivery in conscious, free-moving animal models has broadened the opportunity to study and evaluate the safety and efficacy of these therapeutic products. For the first time, th

chapter 2|36 pages

Physico-chemical factors

chapter 3|12 pages

Vascular infusion dynamics

chapter 4|46 pages

Formulation considerations