ABSTRACT

Intravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or undergoing clinical trials. The technique of prolonged intravenous delivery in conscious, free-moving animal models has broadened the opportunity to study and evaluate the safety and efficacy of these therapeutic products. For the first time, th

chapter 1|24 pages

Body fluid dynamics

chapter 2|36 pages

Physico-chemical factors

chapter 3|12 pages

Vascular infusion dynamics

chapter 4|46 pages

Formulation considerations

chapter |40 pages

Annex: Common excipients and vehicles

chapter |22 pages

Index

chapter |2 pages

Half Title

chapter |1 pages

Title Page

chapter |1 pages

Copyright Page

chapter |2 pages

Contents

chapter |2 pages

Foreword

chapter |4 pages

Preface

chapter 1|56 pages

Rat

chapter 2|60 pages

Mouse

chapter 3|42 pages

Dog

chapter 4|22 pages

Primate

chapter 5|48 pages

Reproductive models

chapter 6|20 pages

Minipig

chapter 7|36 pages

Juvenile animals

chapter 8|22 pages

Marmoset