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Front MatterAbstract - Hi-Res PDF (1089 KB) - PDF w/links (1089 KB)
Chapter 1. Evolutionary Engineering of Industrially Important Microbial PhenotypesStephen S. FongAbstract - Hi-Res PDF (929 KB) - PDF w/links (930 KB)
Chapter 2. Improving Protein Functions by Directed EvolutionNikhil U. Nair, Huimin ZhaoAbstract - Hi-Res PDF (1653 KB) - PDF w/links (1298 KB)
Chapter 3. Engineering DNA and RNA Regulatory Regions through Random Mutagenesis and ScreeningJustin P. Gallivan, Ichiro Matsumura, Sean A. LynchAbstract - Hi-Res PDF (307 KB) - PDF w/links (308 KB)
Chapter 4. Evolving Pathways and Genomes for the Production of Natural and Novel CompoundsEthan T. Johnson, Claudia Schmidt-DannertAbstract - Hi-Res PDF (264 KB) - PDF w/links (274 KB)
Chapter 5. Models Predicting Optimized Strategies for Protein EvolutionPeter Q. Nguyen, Jonathan J. SilbergAbstract - Hi-Res PDF (647 KB) - PDF w/links (609 KB)
Chapter 6. Low-Copy Number Plasmids as Artificial ChromosomesKristala L. Jones PratherAbstract - Hi-Res PDF (352 KB) - PDF w/links (353 KB)
Chapter 7. Chromosomal Engineering StrategiesKenan C. MurphyAbstract - Hi-Res PDF (421 KB) - PDF w/links (421 KB)
Chapter 8. Regulating Gene Expression through Engineered RNA TechnologiesMaung Nyan WinAbstract - Hi-Res PDF (612 KB) - PDF w/links (613 KB)
Chapter 9. Tools Designed to Regulate Translational EfficiencyClaes GustafssonAbstract - Hi-Res PDF (194 KB) - PDF w/links (195 KB)
Chapter 10. Metabolic Engineering of the Secretory Processing Pathway in EukaryotesMohak Mhatre, Michael J. Betenbaugh, Maira P. PellegriniAbstract - Hi-Res PDF (369 KB) - PDF w/links (365 KB)
Chapter 11. Engineering Multifunctional Enzyme Systems for Optimized Metabolite Transfer between Sequential Conversion StepsMatthew P. DeLisa, Robert J. Conrado, Thomas J. MansellAbstract - Hi-Res PDF (353 KB) - PDF w/links (354 KB)
Chapter 12. Practical Pathway Engineering—Demonstration in Integrating ToolsJay D. Keasling, Sung Kuk LeeAbstract - Hi-Res PDF (303 KB) - PDF w/links (310 KB)
Chapter 13. Genome-Wide TechnologiesSang Yup Lee, Seh Hee Jang, Xiao Xia Xia, Jong Hyun Choi, Mee-Jung HanAbstract - Hi-Res PDF (644 KB) - PDF w/links (625 KB)
Chapter 14. Monitoring and Measuring the MetabolomeTomoyoshi Soga, Maria Rowena, N. MontonAbstract - Hi-Res PDF (379 KB) - PDF w/links (305 KB)
Chapter 15. Systems Biology, Genome-Scale Models, and Metabolic EngineeringMarkus J. Herrgård, Jin Sik Kim, Sang Yup Lee, Bernhard Ø. Palsson, Hyun Uk Kim, Vasiliy A. Portnoy, Hongseok Yun, Seung Bum SohnAbstract - Hi-Res PDF (347 KB) - PDF w/links (348 KB)
Chapter 16. Cell-Free Systems for Metabolic EngineeringKara A. Calhoun, James R. SwartzAbstract - Hi-Res PDF (229 KB) - PDF w/links (230 KB)
Chapter 17. In Silico Models for Metabolic Systems EngineeringMasaru Tomita, Kumar Selvarajoo, Satya Nanda Vel ArjunanAbstract - Hi-Res PDF (625 KB) - PDF w/links (616 KB)
Chapter 18. GC–MS for Metabolic Flux AnalysisChristoph WittmannAbstract - Hi-Res PDF (692 KB) - PDF w/links (693 KB)
Chapter 19. Tools for Measuring Intermediate and Product FormationMarco OldigesAbstract - Hi-Res PDF (366 KB) - PDF w/links (367 KB)
Chapter 20. Use Of Aex-Hplc-Esi-Ms For 13C-Labeling Based Metabolic Flux Analysis In Saccharomyces Cerevisiae And Penicillium ChrysogenumWalter M. van Gulik, Wouter A. van Winden, Joseph J. Heijnen, Roelco J. KleijnAbstract - Hi-Res PDF (277 KB) - PDF w/links (278 KB)
Chapter 21. Energy and Cofactor Issues in Fermentation and Oxyfunctionalization ProcessesBirgitta E. Ebert, Lars M. Blank, Bruno Bühler, Andreas Schmid, Katja BühlerAbstract - Hi-Res PDF (942 KB) - PDF w/links (943 KB)
Chapter 22. Microbial Biosynthesis of Fine ChemicalsMattheos Koffas, Zachary L. FowlerAbstract - Hi-Res PDF (452 KB) - PDF w/links (453 KB)
Chapter 23. Applications of Metabolic Engineering for Natural Drug DiscoveryWladyslaw A. Wojcicki, Yi Tang, Suzanne MaAbstract - Hi-Res PDF (467 KB) - PDF w/links (468 KB)
Chapter 24. Metabolic Engineering for Alternative FuelsRamon Gonzalez, Yandi DharmadiAbstract - Hi-Res PDF (289 KB) - PDF w/links (290 KB)
