ABSTRACT

This comprehensive and useful handbook represents a definitive up-to-date compendium of key in vitro bioassay methods that are employed to quantify and validate the anticancer activity of a drug candidate before it makes its way in to animal or clinical trials.

In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development covers the screening and evaluation of potential drug candidates in a wide category of anticancer assays demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules. The major emphasis of the book is to present those bioassays which can be readily set up and practiced in any laboratory with limited funds, facilities or technical know-how.

chapter 3|22 pages

Cell Viability and Cytotoxicity Assays

chapter 4|8 pages

Cell Proliferation Assays

chapter 5|20 pages

Apoptosis Assays

chapter 6|14 pages

Cell Migratory Assays

chapter 7|14 pages

In Vitro Cell Invasion Assays

chapter 8|8 pages

Anti-Angiogenesis Assays

chapter 9|4 pages

High-Throughput Screening Assays