ABSTRACT
While drug therapies developed in the last 50 years have markedly improved the management of some types of cancers, treatment outcomes, and drug side-effects for the most common types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells.
Introduction (inc. Terminologies, Causes of cancer, Mechanisms of genomic damage, Metastases, Treatments); Antimetabolites; DNA-Interactive Agents; Antitubulin Agents; Cell Signaling Inhibitors; Hormonal Therapies; Tumour Targeting Strategies; Biological Agents; The Future; Personalized Medicine (Onocogenomics); Adjunct Therapies; Further Reading section in each Chapter.
