ABSTRACT

Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB is prov

chapter 3|28 pages

Regulation of IKK

chapter 4|34 pages

Control of NF- B Activity by Ubiquitnation

chapter 6|24 pages

NF- B in the Innate Immune System