ABSTRACT

Bringing together the recent and relevant contributions of over 125 scientists from industry, government, and academia in North America and Western Europe, Alternative Toxicological Methods explores the development and validation of replacement, reduction, and refinement alternatives (the 3Rs) to animal testing. Internationally recognized scientist

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PART I Progress in the Validation and Regulatory Acceptance of Alternatives

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PART II Development of Predictive Methods Based on Mechanisms of Eye Irritation at the Ocular Surface: Meeting Industry and Regulatory Needs

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PART III Dermal Testing Alternatives

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PART VI Role of Transgenics and Toxicogenomics in the Development of Alternative Toxicity Tests

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PART VII Recent Innovations in Alternatives

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