ABSTRACT

A tribute to the pioneering scientific work of Professor Koji Nakanishi, whose studies of natural products have effaced some of the conventional boundaries between biology and chemistry. It discusses an array of chromatographic separation methods and determination of structures on a microscale, analyzes bioassay-directed fractionation and other mea

Chapter 1 Insect Antifeeding Limonoids from the Chinaberry Tree Melia azedarach Linn. and Related, Chapter 2 Polygodial and Warburganal, Antifungal Sesquiterpene Dialdehydes and Their Synergists, Chapter 3 Marine Bromoperoxidases— Chemoenzymatic Applications, Chapter 4 LC-Hyphenated Techniques in the Search for New Bioactive Plant Constituents, Chapter 5 Determination of the Absolute Configuration of Biologically Active Compounds by the Modified Mosher’s Method, Chapter 6 Circular Dichroism Spectroscopy and the Absolute Stereochemistry of Biologically Active Compounds, Chapter 7 Recent Applications of Circular Dichroism to Carbohydrate Conformational Analysis and Direct Determination of Drug Levels, Chapter 8 Furan-Terminated Cationic ?-Cyclizations in the Synthesis of Natural Products, Chapter 9 Chemistry and Biology of Semisynthetic Avermectins, Chapter 10 Chemical and Biological Approaches to Molecular Diversity, Chapter 11 Imidazoline Receptors and Their Endogenous Ligands, Chapter 12 Oxidoredox Suppression of Fungal Infections by Novel Pharmacophores, Chapter 13 A Mechanistic Analysis of CEO Bond Cleavage Events with a Comparison to 3,6-Dideoxysugar Formation, Chapter 14 The Molecular Mechanism of Amyloidosis in Alzheimer’s Disease, Chapter 15 Bacteriorhodopsin Structure/ Function Studies, Chapter 16 Autonomous Genomes, Chapter 17 Stereochemical Considerations of Immunoglobulin Heavy Chain Enhancer Activation