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Front MatterAbstract - Hi-Res PDF (649 KB) - PDF w/links (991 KB)
Chapter 1. Glimpses into the Realm of Freeze-DryingAbstract - Hi-Res PDF (378 KB) - PDF w/links (377 KB)
Chapter 2. Structural and Dynamic Properties of Bulk and Con.Ned WaterM.-C. Bellissent-Funel, J. TeixeiraAbstract - Hi-Res PDF (280 KB) - PDF w/links (297 KB)
Chapter 3. Mechanisms of Protein Stabilization during Freeze-Drying and StorageMichael J. PikalAbstract - Hi-Res PDF (374 KB) - PDF w/links (394 KB)
Chapter 4. Freezing and Annealing Phenomena in LyophilizationJames A. SearlesAbstract - Hi-Res PDF (468 KB) - PDF w/links (491 KB)
Chapter 5. Freezing- and Drying-Induced Perturbations of Protein Structure and Mechanisms of Protein Protection by Stabilizing AdditivesTheodore W. Randolph, Ken-ichi Izutsu, John F. CarpenterAbstract - Hi-Res PDF (347 KB) - PDF w/links (375 KB)
Chapter 6. Molecular Mobility of Freeze-Dried Formulations as Determined by Nmr Relaxation, and Its E.Ect on Storage StabilitySumie YoshiokaAbstract - Hi-Res PDF (441 KB) - PDF w/links (457 KB)
Chapter 7. Formulation CharacterizationD. Q. WangAbstract - Hi-Res PDF (638 KB) - PDF w/links (657 KB)
Chapter 8. Practical Aspects of Freeze-Drying of Pharmaceutical and Biological Products Using Non-Aqueous Co-Solvent SystemsDirk L. Teagarden, David S. BakerAbstract - Hi-Res PDF (325 KB) - PDF w/links (337 KB)
Chapter 9. Closure and Container Considerations in LyophilizationFrances L. DeGrazioAbstract - Hi-Res PDF (241 KB) - PDF w/links (253 KB)
Chapter 10. Advanced Glassware for Freeze-DryingJurgen Thurk, Peter KnausAbstract - Hi-Res PDF (341 KB) - PDF w/links (353 KB)
Chapter 11. Critical Steps in the Preparation of Elastomeric Closures for Biopharmaceutical Freeze-Dried ProductsSidney N. Wolfe, Maninder S. HoraAbstract - Hi-Res PDF (187 KB) - PDF w/links (201 KB)
Chapter 12. Development of a New Concept for Bulk Freeze-DryingMeagan GasslerAbstract - Hi-Res PDF (487 KB) - PDF w/links (490 KB)
Chapter 13. Regulatory Control of Freeze-Dried ProductsAbstract - Hi-Res PDF (824 KB) - PDF w/links (872 KB)
Chapter 14. Freeze-Drying of Biological StandardsPaul Matejtschuk, Peter Phillips, Michelle AndersenAbstract - Hi-Res PDF (514 KB) - PDF w/links (523 KB)
Chapter 15. Industrial Freeze-Drying for Pharmaceutical ApplicationsGeorg-Wilhelm OetjenAbstract - Hi-Res PDF (829 KB) - PDF w/links (817 KB)
Chapter 16. Development of Process Data in a Pilot Plant Transferable to ProductionHanna WillemerAbstract - Hi-Res PDF (381 KB) - PDF w/links (384 KB)
Chapter 17. Technical Procedures for Operation of Cleaning-in-Place/Sterilization-in-Place Process for Production Freeze-Drying EquipmentGilles A. BeurelAbstract - Hi-Res PDF (131 KB) - PDF w/links (146 KB)
Chapter 18. Global Validation of Freeze-Drying Cycle Parameters by Using Integral Hft SystemsGilles A. BeurelAbstract - Hi-Res PDF (234 KB) - PDF w/links (242 KB)
Chapter 19. Lyophilizer Quali.CationThorsten FischerAbstract - Hi-Res PDF (398 KB) - PDF w/links (398 KB)
Chapter 20. Lyophilization Process ValidationChristian BindschaedlerAbstract - Hi-Res PDF (338 KB) - PDF w/links (337 KB)
Chapter 21. A New DevelopmentAbstract - Hi-Res PDF (192 KB) - PDF w/links (193 KB)
Chapter 22. Some Leading Edge Prospects in LyophilizationAbstract - Hi-Res PDF (222 KB) - PDF w/links (223 KB)
