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http://dx.doi.org/10.1201/9781420028485
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VII
Front MatterAbstract - Hi-Res PDF (115 KB) - PDF w/links (129 KB)
1
Chapter 1. Dioxygen Activation by Cytochromes P450Alfin D.N. VazAbstract - Hi-Res PDF (269 KB) - PDF w/links (313 KB)
33
Chapter 2. Application of LC/MS, LC/NMR, NMR and Stable Isotopes in Identifying and Characterizing MetabolitesJohn P. Shockcor, A. E. MutlibAbstract - Hi-Res PDF (556 KB) - PDF w/links (504 KB)
87
Chapter 3. BioactivationJack UetrechtAbstract - Hi-Res PDF (528 KB) - PDF w/links (563 KB)
147
Chapter 4. Chemically Reactive Metabolites in Drug Discovery and DevelopmentThomas A. BaillieAbstract - Hi-Res PDF (99 KB) - PDF w/links (119 KB)
155
Chapter 5. Cytochrome P450 and its Place in Drug Discovery and DevelopmentDennis SmithAbstract - Hi-Res PDF (231 KB) - PDF w/links (237 KB)
179
Chapter 6. Cytochrome P450 in Laboratory Animal SpeciesMargit Spatzenegger, Stephanie L. Born, James R. HalpertAbstract - Hi-Res PDF (297 KB) - PDF w/links (353 KB)
211
Chapter 7. Typical and Atypical Enzyme KineticsJ. Brian Houston, Kathryn E. Kenworthy, Aleksandra GaletinAbstract - Hi-Res PDF (552 KB) - PDF w/links (536 KB)
255
Chapter 8. Cytochrome P450 Reaction PhenotypingJeffrey C. Stevens, Larry C. WienkersAbstract - Hi-Res PDF (569 KB) - PDF w/links (585 KB)
311
Chapter 9. Drug-Drug Interactions and the Cytochromes P450Kenneth A. Bachmann, Steven A. Wrighton, Barbara J. RingAbstract - Hi-Res PDF (273 KB) - PDF w/links (298 KB)
337
Chapter 10. CYP Gene Induction by Xenobiotics and DrugsMartine Daujat, Gérard Fabre, Marie-José Vilarem, Lydiane Pichard-Garcia, Lionel Drocourt, Jean-Marc Pascussi, Patrick Maurel, Sylvie Klieber, Martine Bourrié, Sabine Gerbal-Chaloin, François Guillou, François TorreillesAbstract - Hi-Res PDF (308 KB) - PDF w/links (340 KB)
375
Chapter 11. Cytochrome P450 PharmacogeneticsAiming Yu, Robert L. HainingAbstract - Hi-Res PDF (439 KB) - PDF w/links (453 KB)
421
Chapter 12. Role of Intestinal Cytochromes P450 in Drug DispositionKenneth E. Thummel, Mary F. PaineAbstract - Hi-Res PDF (807 KB) - PDF w/links (767 KB)
453
Chapter 13. Prediction of Hepatic Clearance in Humans from Experimental Animals and In Vitro DataMasato Chiba, Yuichi Sugiyama, Yasuyuki Ishii, Hiroyuki Takahashi, Yoshihiro ShibataAbstract - Hi-Res PDF (376 KB) - PDF w/links (399 KB)
483
Chapter 14. Non-P450 Mediated Oxidative Metabolism of XenobioticsDieter Lang, Amit S. KalgutkarAbstract - Hi-Res PDF (538 KB) - PDF w/links (545 KB)
541
Chapter 15. The Role of Sulfotransferases (SULTs) and UDP-Glucuronosyltransferases (UGTs) in Human Drug Clearance and BioactivationMichael W.H. CoughtrieAbstract - Hi-Res PDF (269 KB) - PDF w/links (338 KB)
