ABSTRACT

Maintaining the high standard of quality that made previous editions so successful, this totally revised and updated text incorporates the most recent advances in basic and clinical immunology-emphasizing diagnostic and clinical applications as well as state-of-the-art discussions of the principles and strategies for modulation of the immune respon

Basic Immunology

Introduction
Gabriel Virella
Cells and Tissues Involved in the Immune Response
Gabriel Virella and Jean-Michel Goust
Major Histocompatibility Complex
Jean-Michel Goust
The Induction of an Immune Response: Antigens, Lymphocytes and Accessory Cells
Gabriel Virella and Barbara E. Bierer
Immunoglobulin Structure
Gabriel Virella
Biosynthesis, Metabolism, and Biological Properties of Immunoglobulins
Gabriel Virella
Genetics of Immunoglobulins
Janardan P. Pandey
Antigen-Antibody Reactions
Gabriel Virella
The Complement System
Robert Boackle
Lymphocyte Ontogeny and Membrane Markers
Virginia M. Litwin and Jean-Michel Goust
Cell-Mediated Immunity
Barbara E. Bierer, Jean-Michel Goust, and Gabriel Virella
The Humoral Immune Response and Its Induction by Active Immunization
Gabriel Virella
Phagocytic Cells
Gabriel Virella
Infections and Immunity
Gabriel Virella

Diagnostic Immunology

Diagnostic Immunology
Gabriel Virella and Virginia M. Litwin

Clinical Immunology

Tolerance and Autoimmunity
George C. Tsokos, Jean-Michel Goust, and Gabriel Virella
Organ-Specific Autoimmune Diseases
Gabriel Virella and Jean-Michel Goust
Systemic Lupus Erythematosus
George C. Tsokos and Jean-Michel Goust
Rheumatoid Arthritis
Jean-Michel Goust and Gabriel Virella
Hypersensitivity Reactions
Gabriel Virella
IgE-Mediated (Immediate) Hypersensitivity
Jean-Michel Goust and Albert F. Finn, Jr.
Immunohematology
Gabriel Virella and Mary Ann Spivey
Immune Complex Diseases
Gabriel Virella and George C. Tsokos
Immune System Modulators
Philip D. Hall, Jean-Michel Goust, and Gabriel Virella
Transplantation Immunology
Gabriel Virella, Richard Knight, and Jonathan Bromberg
Tumor Immunology
Sebastiano Gattoni-Celli
Malignancies of the Immune System
Gabriel Virella and Jean-Michel Goust

Immunodeficiency Disea