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http://dx.doi.org/10.1201/9780824741990
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Front MatterAbstract - Hi-Res PDF (372 KB) - PDF w/links (372 KB)
Chapter 1. History and Physiology of the Blood–Brain Barrier in Relation to Delivery of Drugs to the BrainAbstract - Hi-Res PDF (66 KB) - PDF w/links (68 KB)
Chapter 2. Physicochemical Factors that Influence Brain UptakeJames A. Platts, Michael H. AbrahamAbstract - Hi-Res PDF (142 KB) - PDF w/links (164 KB)
Chapter 3. The Development of In Vitro Models for the Blood–Brain and Blood–CSF BarriersDorothea Korte, Helmut Franke, Joachim Wegener, Matthias Haselbach, Hans-Joachim Galla, Thorsten Nitz, Christiane EngelbertzAbstract - Hi-Res PDF (464 KB) - PDF w/links (401 KB)
Chapter 4. In Vitro Models of the Blood–Brain Barrier and Their Use in Drug DevelopmentC. Duhem, V. Buee-Scherrer, B. Dehouck, R. Cecchelli, M. P. Dehouck, L. Descamps, L. Fenart, G. TorpierAbstract - Hi-Res PDF (86 KB) - PDF w/links (106 KB)
Chapter 5. The Application of Microdialysis Techniques to the Study of Drug Transport Across the Blood–Brain BarrierA. G. de Boer, Inez C. J. van der Sandt, Elizabeth C. M. de Lange, Douwe D. BreimerAbstract - Hi-Res PDF (111 KB) - PDF w/links (129 KB)
Chapter 6. The Role of Brain Extracellular Fluid Production and Efflux Mechanisms in Drug Transport to the BrainAnthony Regina, Francoise Roux, Christopher Rollinson, Joan Abbott, Ehsan Ullah KhanAbstract - Hi-Res PDF (177 KB) - PDF w/links (177 KB)
Chapter 7. The Relevance of P-Glycoprotein in Drug Transport to the BrainUlrich MayerAbstract - Hi-Res PDF (90 KB) - PDF w/links (109 KB)
Chapter 8. Specific Mechanisms for Transporting Drugs Into BrainAkira TsujiAbstract - Hi-Res PDF (161 KB) - PDF w/links (181 KB)
Chapter 9. Drug Metabolism in the BrainRamon D.S. El-Bacha, Philippe Lagrange, Daniela Gradinaru, Funmilayo G. Suleman, Alain Minn, Claire Bayol-DenizotAbstract - Hi-Res PDF (155 KB) - PDF w/links (174 KB)
Chapter 10. Targeting Macromolecules to the Central Nervous SystemUlrich BickelAbstract - Hi-Res PDF (193 KB) - PDF w/links (208 KB)
Chapter 11. Using Nanoparticles to Target Drugs to the Central Nervous SystemRenad N. Alyautdin, Jorg KreuterAbstract - Hi-Res PDF (121 KB) - PDF w/links (139 KB)
Chapter 12. Basic CNS Drug Transport and Binding Kinetics In VivoDonald Frederick Smith, Antony D. Gee, Albert GjeddeAbstract - Hi-Res PDF (121 KB) - PDF w/links (139 KB)
