ABSTRACT

DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topi

chapter |13 pages

NUCLEOTIDE EXCISION REPAIR (NER)

chapter |4 pages

ACKNOWLEDGEMENTS

chapter |4 pages

REFERENCES

chapter |2 pages

IONIZING RADIATION

chapter |2 pages

DNA IS THE CRITICAL TARGET

chapter |4 pages

TYPES OF DNA DAMAGE

chapter |26 pages

Non‐DSB clusters

A. Tandem

chapter |10 pages

ACKNOWLEDGEMENTS

chapter |8 pages

ACKNOWLEDGEMENT

chapter |18 pages

BIOCHEMICAL MODEL OF HUMAN MMR

chapter |31 pages

APE1 Gene and Protein

chapter |7 pages

REFERENCES

chapter |14 pages

p53 AND NONCODING RNA

chapter |25 pages

WILD-TYPE p53 ACTIVATION IN CANCER

chapter |32 pages

ATM/ATR ACTIVATION

chapter |9 pages

CONCLUSIONS

chapter |2 pages

Preclinical Studies

chapter |30 pages

REFERENCES

chapter |11 pages

REFERENCES

chapter |6 pages

Color Plate Section

chapter 2|2 pages

Color Plate Section

chapter 12|4 pages

Chapter 12

chapter 17|3 pages

Chapter 17