ABSTRACT
In this chapter, the author introduces the concept of intrinsic disorder in proteins and how this impacts protein function and biomineralization. He deals with a look into the future and what they expect to happen in the intrinsically disordered proteins (IDP) field and how this will impact the biomineralization field. Compared to scientific fields, our understanding of biomineralization protein structure and how it contributes to function has not made sufficient progress. A disordered biomineralization protein or protein assembly may possess Polymer induced liquid precursor (PILP)-like molecular characteristics as a result of the labile, unstable sequence regions that exist in the primary sequence of these proteins. These PILP systems integrate very well with the nonclassical nucleation scheme that involves the formation of prenucleation clusters from supersaturated solution. One of the major problems with experimental approaches is the time that it takes to acquire data.
