ABSTRACT

Abstract .................................................................................................................. 145 Keywords ............................................................................................................... 146 8.1Introduction .................................................................................................. 146 8.2Structural Features Associated with Juvenile Hormone Activity ................ 147 8.3SAR Models for Detecting Juvenile Hormone Mimics ................................ 150 8.4 2D QSAR Models for Predicting Juvenile Hormone Activity ..................... 151 8.5Conclusions ................................................................................................... 171 Acknowledgment................................................................................................... 172 References.............................................................................................................. 172

SAR, QSAR, Juvenile hormone mimics, Linear regression, Nonlinear techniques

By the end of World War II, drastic changes in farming practice were observed in different parts of the world but especially in North America, Australia, and western Europe. Tractors have replaced horses, and chemical fertilizers were increasingly used in place of organic manure. Use of synthetic pesticides became widespread. Farmers were encouraged to stop crop rotation and to devote large acreages of their farms to the cultivation of a single crop, which undoubtedly required the use of increasing quantities of synthetic fertilizers and pesticides.