ABSTRACT

The basic principle of tissue engineering entails the guided application and the control of cells, materials, and the microenvironment into which they are delivered [1]. In a tissue engineering process, tissues or organs may be created in vivo, in vitro, or ex vivo and implanted into the patient [2]. In this direction, the selection of three elements rstly concurs to satisfy the basic tissue engineering principles on fabricating biological tissues: (i) viable, responsive cells; (ii) a scaffold to support tissue formation; and (iii) a growth-inducing stimulus.