ABSTRACT

Therefore, we aimed to study whether and how bioaccessibility of As from rice is affected by diet composition. An Asian diet (Suhana et al. 1999; Park et al. 2006) was compared with a Western diet (Suhana et al. 1999; Park et al. 2006). Bioaccessiblity was assessed by simulating gastro-intestinal digestion in vitro using the IVG (in vitro gastrointestinal) method with slight modifications. The role of micro-organisms in the colon was studied using the Simulator of the Human Intestinal Microbial Ecosystem (SHIME) (Van De Wiele et al. 2010).