ABSTRACT

For twenty-five years, Dermatotoxicology has stood as the definitive reference book in the field. A generation of toxicologists and dermatologists has consulted this volume throughout their careers, finding within it a wealth of theoretical and practical guidance.

Updated and expanded to reflect the latest developments in skin toxicology, De

part |2 pages

PART I: Concepts

chapter 1|10 pages

Skin Permeability

chapter 2|16 pages

Occlusion and Barrier Function

chapter 5|12 pages

Percutaneous Absorption: Role of Lipids

chapter 8|14 pages

Sensitive Skin

chapter 10|30 pages

Iontophoresis

chapter 11|48 pages

Irritant Dermatitis (Irritation)

chapter 12|8 pages

Allergic Contact Dermatitis

chapter 15|36 pages

System Contact Dermatitis

chapter 18|22 pages

Chemically Induced Scleroderma

chapter 19|14 pages

Chemical Agents that Cause Depigmentation

chapter 20|20 pages

Sulfar Mustard: A Chemical Vesicant Model

chapter 22|22 pages

Retinoids and Their Mechanisms of Toxicity

chapter 24|22 pages

Drug Induced Ocular Phototoxicity

chapter 25|8 pages

Water: Is It an Irritant?

chapter 26|28 pages

Sodium Lauryl Sulfate in Dermatotoxitcology

chapter 27|10 pages

Barrier Creams

part |2 pages

PART II: Methods

chapter 28|12 pages

Methods for In Vitro Percutaneous Absorption

chapter 29|18 pages

Tape Stripping Method and Stratum Corneum

chapter 31|26 pages

Isolated Perfused Porcine Skin Flap

chapter 33|10 pages

Methods for In Vitro Skin Metabolism Studies

chapter 41|24 pages

The Local Lymph Node Assay

chapter 51|66 pages

Cosmetic Reactions